Ovidrel

Ovidrel is a recombinant human chorionic gonadotropin (r-hCG) medication used primarily in fertility treatments. It is designed to trigger ovulation in women undergoing assisted reproductive techniques like IVF (in vitro fertilization), IUI (intrauterine insemination), or timed intercourse.

Key Uses of Ovidrel

• In Women:

  • Triggers ovulation by mimicking the luteinizing hormone (LH) surge.

  • Supports the final maturation of eggs before retrieval in IVF.

• Not typically used in men, unlike Novarel or Pregnyl, which can treat male infertility.

Dosage & Administration

• Given as a subcutaneous (SC) injection, usually in the abdomen or thigh.

• Common dose: 250 mcg injection, taken about 36 hours before ovulation or egg retrieval.

• Comes in a pre-filled syringe for easier administration.

Side Effects

• Mild pain, redness, or swelling at the injection site

• Bloating, nausea, or headache

• Breast tenderness

• Risk of ovarian hyperstimulation syndrome (OHSS), which can cause severe bloating, weight gain, and fluid buildup

• Increased chances of multiple pregnancies

Ovidrel vs. Novarel (hCG) Differences

• Ovidrel is recombinant hCG, while Novarel is derived from urine-derived hCG.

• Ovidrel is injected subcutaneously, while Novarel is given intramuscularly.

• Ovidrel is often preferred for its convenience (pre-filled syringe, easier injection).