Menotropins

Menotropins, also known as human menopausal gonadotropins (hMG), are a type of fertility medication that contains a combination of follicle-stimulating hormone (FSH) and luteinizing hormone (LH). They are extracted from the urine of postmenopausal women and are used to stimulate ovulation in individuals with fertility issues.

Uses of Menotropins

1. Ovulation Induction – Helps women who do not ovulate regularly or have conditions like polycystic ovary syndrome (PCOS).

2. Controlled Ovarian Hyperstimulation (COH) – Used in assisted reproductive technologies like in vitro fertilization (IVF) to promote multiple follicle development.

3. Male Infertility – Sometimes prescribed to men with low sperm count due to hypogonadotropic hypogonadism.

How It Works

• FSH promotes the growth and maturation of ovarian follicles in women.

• LH triggers ovulation and supports corpus luteum function.

• In men, these hormones stimulate testosterone production and sperm development.

Administration

• Usually given via subcutaneous or intramuscular injection.

• Dosage and duration depend on the patient’s response, monitored by blood tests and ultrasound.

Common Brand Names

• Menopur

• Repronex

• Pergonal (discontinued in some markets) (The Pergonal brand name has been discontinued in the U.S.)

Side Effects

• Injection site reactions (pain, swelling, redness)

• Ovarian hyperstimulation syndrome (OHSS)

• Multiple pregnancies (twins, triplets, or more)

• Abdominal discomfort, bloating

• Mood swings, headaches